LABORATORY FEATURES OF ACUTE VIRAL HEPATITIS IN THE REPUBLIC OF KARAKALPAKSTAN

Abstract

Relevance of the topic. In the Republic of Karakalpakstan, a region in northwest Uzbekistan, AVH is a pressing public health concern due to a combination of socio-environmental factors such as limited access to safe drinking water, suboptimal sanitation, and gaps in vaccination coverage. The region has reported sporadic outbreaks of HAV and HEV, alongside a steady prevalence of HBV infections, reflecting both environmental exposure and healthcare-related factors. Despite the high burden of disease, there is a lack of comprehensive data on the clinical presentations and laboratory profiles of AVH patients in Karakalpakstan. Understanding the clinical and laboratory characteristics of AVH is crucial for early diagnosis, effective treatment, and the development of targeted preventive strategies. This study aims to systematically evaluate the clinical features and laboratory parameters of patients with acute viral hepatitis in Karakalpakstan, providing insights into regional epidemiology, disease severity, and implications for public health interventions.