MORPHOLOGICAL CHANGES OF THE LUNGS IN EXPERIMENTAL ATHEROSCLEROSIS

Abstract

Annotation. It has been established that patients with Chronic Obstructive Pulmonary Disease die more often from cardiovascular causes than from Chronic Obstructive Pulmonary Disease itself, and coronary heart disease (CHD) is the leading cause of death. The morphological substrate of CHD is atherosclerotic plaque (AP), and numerous studies have been published assessing and comparing the degree of atherosclerotic lesions in the coronary arteries in patients with CHD and COPD using multislice computed tomography of the heart [6–8] and invasive coronary angiography (CAG).The study of changes in lung tissue in atherosclerosis is undoubtedly one of the urgent problems of modern morphology. Atherosclerosis is a systemic process, therefore, if damage is detected in one part of the body, the likelihood of atherosclerosis developing in other areas, including the lungs, is very high. In atherosclerosis, as a systemic disease, changes in the lungs can manifest as narrowing of the pulmonary arteries due to the formation of atherosclerotic plaques, which leads to impaired function and the development of symptoms such as shortness of breath.