CELLULAR COMPOSITION OF LYMPHOID STRUCTURES OF THE APPENDIX MUCOSA IN ADULTS

Abstract

In addition to local immune control, intestinal lymphoid tissue is functionally integrated into the general immune system of the human body [1]. The immune system, through feedback [2], influences the nervous and endocrine systems, thus serving as a general regulatory system. The development of lymphoid structures and their number changes with age [3–4]. The number of these structures in the walls of different sections of the colon [3, 5–6] and their response to stimuli [7–9] have been established. The intercellular relationships and quantitative composition of immune cell populations in the lymphoid structures of the intestinal wall, as well as their age-related restructuring, remain poorly understood.