MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS AND CLINICAL EVALUATION OF BRAIN TUMORS: A STUDY BASED IN UZBEKISTAN
Keywords:
Keywords: MRI, Brain Tumors, DCE-MRI, DWI, Glioblastoma, Meningioma, Diagnosis, Neuroimaging, Uzbekistan, Tumor Perfusion, Tumor CellularityAbstract
Abstract: Brain tumors present complex diagnostic and therapeutic
challenges, necessitating an integrated approach that combines clinical expertise
with advanced neuroimaging techniques. Magnetic Resonance Imaging (MRI) has
emerged as a cornerstone modality for the evaluation of intracranial neoplasms,
offering non-invasive, high-resolution visualization of brain structures. This study,
conducted at the Republican Specialized Neurosurgery Scientific and Practical
Medical Center in Tashkent, Uzbekistan, aimed to evaluate the diagnostic
accuracy of MRI, with a focus on advanced imaging modalities such as Dynamic
Contrast-Enhanced MRI (DCE-MRI) and Diffusion-Weighted Imaging (DWI), in
differentiating benign from malignant brain lesions. Over a one-year period
(2023–2024), MRI scans of 129 patients were reviewed. Results demonstrated
high sensitivity (92%) and specificity (86%) for malignant tumor detection.
Enhanced diagnostic precision was achieved through DCE-MRI and DWI, which
improved tissue characterization by assessing perfusion dynamics and cellular
density. These findings support the vital role of MRI in early detection, treatment
planning, and prognosis evaluation in neuro-oncology.
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