THE PHYSIOLOGY OF CONNECTIVE TISSUE AND ITS INHIBITION IN THE NERVOUS SYSTEM

Abstract

Connective tissue plays a crucial role in maintaining the structural integrity and physiological function of the nervous system. It serves not only as a supportive framework for neural cells but also impacts signaling processes essential for neural communication. Emerging research indicates that the oversaturation of matrix components can lead to pathophysiological conditions, such as fibrosis, which affects neurotransmission and contributes to chronic pain syndromes (Langevin & Sherman, 2007). Furthermore, the relationship between connective tissues and neuroglial cells emphasizes a complex interaction where glial response to injury may modify the surrounding extracellular matrix, thus influencing neuron behavior and repair mechanisms. The implications of these interactions are particularly relevant in systemic conditions such as systemic sclerosis, where gastrointestinal dysmotility is observed due to altered connective tissue dynamics (Abraham et al., 2017). Understanding these physiological and pathological processes is essential for developing targeted therapeutic strategies to mitigate nervous system dysfunction.