STEATOZ BILAN KECHUVCHI SURUNKALI GEPATIT C NING KLINIK-LABORATORIYA VA INSTRUMENTAL XUSUSIYATLARI
Abstract
Mavzuning dolzarbligi. Metabolik disfunksiya bilan bog'liq steatotik jigar kasalligi semirish epidemiyasi tufayli butun dunyo bo'ylab eng keng tarqalgan surunkali jigar kasalligiga aylandi[1-5]. So'nggi hisob kitoblarga ko'ra, asoslangan global aholining deyarli uchdan biriga ta'sir qiladi [6-8]. Gepatit C (HCV) - bu gepatotrop virus bo'lib, jigar metabolizmini buzadi va jigarning progressiv shikastlanishiga olib keladi [9-15].C gepatitning steatoz bilan kechuvchi surunkali shakli - bu jigarning surunkali yallig'lanish jarayoni bo'lib, unda jigar hujayralarida yog' to'planishi (steatoz) yuz berishi mumkin [16-21]. Odamlarda gepatit C virusi (HCV) genotipi 3 ko'proq steatoz bilan bog'liq [22-27]. Steatoz bilan kechuvchi surunkali C gepatitida quyidagi klinik alomatlar kuzatilishi mumkin:bemorlar ko'pincha charchoq, tavsiflanmagan og'riq va qorin sohasida noqulaylik his qilishadi [28-32]. Ba'zi hollarda, ularning terisida sarg'ayish paydo bo'lishi mumkin.
Ishning maqsadi. steatoz fibrozning rivojlanishi bilan bog'liq bo'lishi mumkin va bu genotipga xos bo'lishi mumkinligini klinik-laboratoriya va instrumental tekshiruvlar orqali o’rganish.
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