SURGICAL TREATMENT OF UPPER GASTROINTESTINAL BLEEDING: A SIMPLIFIED REVIEW

Authors

  • Uroqov Sh.T. Author
  • Mansoor Ahmad Author

Keywords:

Key words: Upper gastrointestinal bleeding, esophageal varices, peptic ulcer disease, medication, surgery, blood loss

Abstract

Abstract: Upper gastrointestinal bleeding (UGIB) is a medical emergency that can be life-threatening, especially in older patients and those with other health problems. While most cases can be managed with medications and endoscopy, around 10-15% require surgery when other treatments don’t work. This review covers when and why surgery is needed for UGIB, the types of surgical procedures used, comparisons with other non-surgical treatments, and newer techniques that are being developed. The goal is to provide a clear understanding of the role of surgery in treating UGIB based on the latest evidence.

References

1. Oakland K.Changing epidemiology of upper gastrointestinal hemorrhage in the 21st century. Clin Gastroenterol Hepatol. 2022;20(6):e1065-e1080.

2. Wuerth BA, Rockey DC. Changing epidemiology of upper GI hemorrhage in the US. JAMA Intern Med. 2018;178(3):421-422.

3. Swain CP. The history of endoscopic hemostasis. Gastrointest Endosc Clin N Am. 2015;25(3):xiii-xviii.

4. Lau JYW. Timing of endoscopy for acute upper GI bleeding. N Engl J Med. 2020;382(14):1299-1308.

5. Khamaysi I. Epinephrine plus second modality vs epinephrine alone: meta-analysis. Gastrointest Endosc. 2021;93(4):AB123.

6. Gralnek IM. Ethanol injection risks in gastric ulcers. Endoscopy. 2019;51(8):734-741.

7. Barkun AN. Cost-effectiveness of fibrin glue. Am J Gastroenterol. 2020;115(3):412-420.

8. Jensen DM. BICAP vs heater probe: multicenter RCT. Clin Gastroenterol Hepatol. 2018;16(5):679-687.

9. Suzuki N. APC depth penetration study. Endosc Int Open. 2022;10(3):E215-E221.

10. Park CH. Dieulafoy lesion outcomes. Gut Liver. 2021;15(2):256-263.

11. Sung JJY. Clip therapy for Forrest Ia. Lancet Gastroenterol Hepatol. 2019;4(10):790-798.

12. Schmidt A. OTSC registry data. Endoscopy. 2020;52(9):769-776.

13. Chen YI. TC-325 cost-effectiveness. Gastrointest Endosc. 2023;97(1):134-142.

14. de Franchis R. EVL vs sclerotherapy: Baveno VII. J Hepatol. 2022;77(1):179-190.

REFERENCES

1. Barkun, A. N., Bardou, M., Kuipers, E. J., Sung, J., Hunt, R. H., Martel, M., ... & International Consensus Upper Gastrointestinal Bleeding Conference Group*. (2010). International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding. Annals of internal medicine, 152(2), 101-113.

2. [ ] Cook, D. J., Fuller, H. D., Guyatt, G. H., Marshall, J. C., Leasa, D., Hall, R., ... & Willan, A. (1994). Risk factors for gastrointestinal bleeding in critically ill patients. New England journal of medicine, 330(6), 377-381.

3. [ ] Gutthann, S. P., GarcíaRodríguez, L. A., & Raiford, D. S. (1997). Individual nonsteroidal antiinflammatory drugs and other risk factors for upper gastrointestinal bleeding and perforation. Epidemiology, 8(1), 18-24.

4. [ ] Tielleman, T., Bujanda, D., & Cryer, B. (2015). Epidemiology and risk factors for upper gastrointestinal bleeding. Gastrointestinal Endoscopy Clinics, 25(3), 415-428.

5. [ ] Johnsen, S. P., Sørensen, H. T., Mellemkjœr, L., Blot, W. J., Nielsen, G. L., McLaughlin, J. K., & Olsen, J. H. (2001). Hospitalisation for upper gastrointestinal bleeding associated with use of oral anticoagulants. Thrombosis and haemostasis, 86(08), 563-568.

6. [ ] Cerini, F., Gonzalez, J. M., Torres, F., Puente, Á., Casas, M., Vinaixa, C., ... & Garcia‐Pagán, J. C. (2015). Impact of anticoagulation on upper‐gastrointestinal bleeding in cirrhosis. A retrospective multicenter study. Hepatology, 62(2), 575-583.

7. [ ] Lee, M. W., & Katz, P. O. (2021). Nonsteroidal antiinflammatory drugs, anticoagulation, and upper gastrointestinal bleeding. Clinics in Geriatric Medicine, 37(1), 31-42.

8. [ ] Ibanez, L., Vidal, X., Vendrell, L., Moretti, U., Laporte, J. R., & SPANISH–ITALIAN COLLABORATIVE GROUP FOR THE EPIDEMIOLOGY OF GASTROINTESTINAL BLEEDING. (2006). Upper gastrointestinal bleeding associated with antiplatelet drugs. Alimentary pharmacology & therapeutics, 23(2), 235-242.

9. [ ] Lanas, A., & Scheiman, J. (2007). Low-dose aspirin and upper gastrointestinal damage: epidemiology, prevention and treatment. Current medical research and opinion, 23(1), 163-173.

10. [ ] Fletcher, E. H., Johnston, D. E., Fisher, C. R., Koerner, R. J., Newton, J. L., & Gray, C. S. (2010). Systematic review: Helicobacter pylori and the risk of upper gastrointestinal bleeding risk in patients taking aspirin. Alimentary pharmacology & therapeutics, 32(7), 831-839.

11. [ ] Liberopoulos, E. N., Elisaf, M. S., Tselepis, A. D., Archimandritis, A., Kiskinis, D., Cokkinos, D., & Mikhailidis, D. P. (2006). Upper gastrointestinal haemorrhage complicating antiplatelet treatment with aspirin and/or clopidogrel: where we are now?. Platelets, 17(1), 1-6.

12. [ ] de Abajo, F. J., Rodríguez, L. A. G., & Montero, D. (1999). Association between selective serotonin reuptake inhibitors and upper gastrointestinal bleeding: population based case-control study. Bmj, 319(7217), 1106-1109.

13. [ ] Anglin, R., Yuan, Y., Moayyedi, P., Tse, F., Armstrong, D., & Leontiadis, G. I. (2014). Risk of upper gastrointestinal bleeding with selective serotonin reuptake inhibitors with or without concurrent nonsteroidal anti-inflammatory use: a systematic review and meta-analysis. Official journal of the American College of Gastroenterology| ACG, 109(6), 811-819.

14. [ ] Rahman, A. A., He, N., Rej, S., Platt, R. W., & Renoux, C. (2022). Concomitant use of selective serotonin reuptake inhibitors and oral anticoagulants and risk of major bleeding: a systematic review and meta-analysis. Thrombosis and Haemostasis.

15. [ ] Alam, S. M., Qasswal, M., Ahsan, M. J., Walters, R. W., & Chandra, S. (2022). Selective serotonin reuptake inhibitors increase risk of upper gastrointestinal bleeding when used with NSAIDs: a systemic review and meta-analysis. Scientific Reports, 12(1), 14452.

Published

2025-05-12

How to Cite

Uroqov Sh.T., & Mansoor Ahmad. (2025). SURGICAL TREATMENT OF UPPER GASTROINTESTINAL BLEEDING: A SIMPLIFIED REVIEW. JOURNAL OF NEW CENTURY INNOVATIONS, 76(1), 527-532. https://scientific-jl.com/new/article/view/13135