HISTOLOGICAL AND NEUROENDOCRINE MECHANISMS OF PREMENSTRUAL SYNDROME: A CLINICAL AND MICROSCOPIC PERSPECTIVE
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Key words: Premenstrual syndrome (PMS), Hormonal fluctuations, Estrogen, Progesterone, Histological changes, Neuroendocrine mechanisms, Menstrual cycle, GABA receptors, Serotonin, Endometrial inflammation.##article.abstract##
Abstract: Premenstrual syndrome (PMS) affects a majority of women during their reproductive years, with symptoms that extend beyond mood swings to include histologically rooted changes. This article explores the interplay between hormonal fluctuations and tissue-level responses in the brain and reproductive system. Using both personal observations and academic literature, the study identifies how estrogen, progesterone, and neurotransmitters like serotonin contribute to PMS. Through this dual analysis, we highlight the biological basis of symptoms often dismissed as minor. Diagrams and tables are included to aid in visualizing these complex mechanisms. This paper aims to provide both scientific insight and practical understanding of PMS
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