ACCELERATION OF TISSUE REGENERATION THROUGH THE USE OF MAGNETICALLY ACTIVATED BIOMATERIALS

Аннотация

Abstract: Tissue regeneration is a critical component of modern biomedical therapies, particularly in cases involving injury, surgery, or degenerative diseases. Recent advances in biomaterials science have led to the development of magnetically activated biomaterials, which offer a promising strategy for enhancing tissue repair processes. These smart materials are designed to respond to external magnetic fields, enabling controlled stimulation of cellular activities such as proliferation, differentiation, and alignment. By incorporating magnetic nanoparticles into scaffolds, hydrogels, or drug delivery systems, researchers have achieved localized and non-invasive activation of regenerative responses. Furthermore, magneto-mechanical stimulation has been shown to enhance angiogenesis and extracellular matrix formation, both of which are essential for effective tissue healing. This paper reviews current developments in magnetically responsive biomaterials, their mechanisms of action, and their potential applications in bone, nerve, and muscle tissue engineering. The study also discusses the challenges of biocompatibility, field penetration, and clinical translation, highlighting future research directions for creating more efficient and personalized regenerative therapies.