THE ROLE OF IMMUNOLOGICAL PARAMETERS IN PREDICTING CEREBRAL PALSY IN YOUNG CHILDREN

Abstract

Current data indicate the involvement of immune mechanisms in the pathogenesis of many diseases. The importance of cellular and humoral factors of the immune system in patients with hypoxic-ischemic lesions of the central nervous system and their consequences, including cerebral palsy, is shown. At the same time, special attention is paid to individual cytokines as markers of neurodestructive and neuro-reparative processes, among which many researchers assign the main role to tumor necrosis factor-a (TNF-a). In recent years, researchers have been increasingly interested in studying the clinical and immunological mechanisms of the formation and progression of cerebral palsy. This review summarizes current data on clinical factors, immunological markers, and their prognostic significance in assessing the course of cerebral palsy in young children