IMPACT OF ANTIHYPERTENSIVE MEDICATIONS ON INSULIN RESISTANCE AND LIPID PROFILE MODULATION
Keywords:
Arterial hypertension, metabolic syndrome, lipid spectrum, HOMA index , insulin resistance.Abstract
The mechanism of developing arterial hypertension and insulin resistance in individuals with excess body weight is of great importance when determining the treatment strategy, including the selection of medications, dosage, and duration of use, as well as the combination of antihypertensive agents, statins, biguanides, insulin medications, and hepatoprotective and cardioprotective agents. In this regard, antihypertensive drugs, such as losartan and nebivolol, used to treat patients with excess body weight and/or insulin resistance, must meet several criteria: effectively reduce blood pressure throughout the da, have no adverse effects on
carbohydrate, lipid, and purine metabolism, possess organoprotective effects, and reduce the risk of developing metabolic syndrome (MS).
References
1.
3
Abdulloyeva , M., Pulatova , K., & Mirzaev , R. (2023). ORTIQCHA VAZN
VA ARTERIAL GIPERTONIYA BILAN OG'RIGAN YOSHLARDA YUZAGA
KELADIGAN JINSIY ZAIFLIK. Eurasian Journal of Medical and Natural Sciences
,
(4
Part
2),
91–94.
academy.uz/index.php/EJMNS/article/view/135152.
Bakhtiyarovich A. A., Samvelovna P. K. Peculiarities of the Influence of
Metabolic Syndrome on the Course of Coronary Heart Disease //American Journal of
Pediatric Medicine and Health Sciences (2993-2149). – 2023. – Т. 1. – №. 8. – С. 396
400.
3.
Dilshodovna , A. M., Odylovna , K. F., & Samveilovna , P. K. (2022).
Peculiarities of Psychological Disorders in Patients with Acute Coronary Syndrome.
INTERNATIONAL JOURNAL OF HEALTH SYSTEMS AND MEDICAL SCIENCES ,
1
(6),
203–207.
Retrieved
publishing.com/index.php/IJHSMS/article/view/695
4.
from http://inter
Kristina Samvelovna Pulatova , Timur Mukhitdinovich Pulatov , Mukhammad
Olimovich Esankulov THE SPECIFIC FEATURES OF ARTERIAL
HYPERTENSION IN OWERWEIGHT PATIENTS WITH PSORIASIS // Academic
research
in
educational
sciences.
2021.
No.
2.
URL:
https://cyberleninka.ru/article/n/the-specific-features-of-arterial-hypertension-in
owerweight-patients-with-psoriasis (access date: 05/13/2023).
5.
Nasyrova Zarina Akbarovna , Abdulloeva Maftuna Dilshodovna , Usarov
Shohruh Abduvahob Ugli STRATIFICATION OF RISK FACTORS IN CORONARY
HEART
DISEASE
//
JCRR.
2021.
No.
3.
URL:
https://cyberleninka.ru/article/n/stratifikatsiya-faktorov-riska-pri-ishemicheskoy
bolezni-serdtsa (date of access: 05/13/2023).
6.
Pulatova K. Analysis of Ecg and Echo Results in Hypertensive Patients
Depending on Bmi Degrees //International Journal of Health Systems and Medical
Sciences. –
2023.https://cajmns.centralasianstudies.org/index.php/CAJMNS/article/view/1193
7.
Пулатова К. ИЗМЕНЕНИЯ ГЕМОДИНАМИЧЕСКИХ ПОКАЗАТЕЛЕЙ
БОЛЬНЫХ С ИЗБЫТОЧНЫМ ВЕСОМ ПРИ ИШЕМИЧЕСКОЙ БОЛЕЗНИ
СЕРДЦА //Евразийский журнал медицинских и естественных наук. – 2024. – Т.
4. – №. 1. – С. 68-71.
