OSHQOZON OSTI BEZI RAKI: ETIOLOGIYASI, KLINIK BELGILARI VA DAVOLASH USULLARI
Keywords:
oshqozon osti bezi raki, pankreatik adenokarsinoma, xavf omillari, CA 19-9, Whipple operatsiyasi, gemoterapiya, skrining.Abstract
Oshqozon osti bezi raki (pankreatik adenokarsinoma) dunyo bo‘yicha o‘lim darajasi
eng yuqori bo‘lgan onkologik kasalliklardan biri hisoblanadi. Kasallikning kech
aniqlanishi va o‘smaning invaziv xususiyatlari davolashning murakkabligi va past
samaradorligiga olib keladi. Mazkur maqolada pankreatik rakning etiologiyasi, xavf
omillari, klinik belgilari, diagnostik usullari, zamonaviy davolash strategiyalari va
prognozi atroflicha tahlil qilinadi. Ilmiy manbalar asosida, kasallikka qarshi kurashda
profilaktika va erta tashxislash muhimligi asoslab beriladi.
References
1. Siegel R.L., Miller K.D., Jemal A. (2020). Cancer statistics, 2020. CA: A Cancer
Journal for Clinicians, 70(1): 7–30. doi:10.3322/caac.21590.
2. Kleeff J., Korc M., Apte M., et al. (2016). Pancreatic cancer. Nature Reviews
Disease Primers, 2: 16022. doi:10.1038/nrdp.2016.22.
3. Rahib L., Smith B.D., Aizenberg R., et al. (2014). Projecting cancer incidence and
deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the
United States. Cancer Research, 74(11): 2913–2921. doi:10.1158/0008-5472.CAN-14
0155.
4.
Tempero M.A., Malafa M.P., Al-Hawary M., et al. (2021). Pancreatic
Adenocarcinoma, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.
Journal of the National Comprehensive Cancer Network, 19(4): 439–457.
doi:10.6004/jnccn.2021.0017.
5. Rawla P., Sunkara T., Gaduputi V. (2019). Epidemiology of Pancreatic Cancer:
Global Trends, Etiology and Risk Factors. World Journal of Oncology, 10(1): 10–27.
doi:10.14740/wjon1166.
6. O‘zbekiston Respublikasi Sog‘liqni saqlash vazirligi. (2023). Onkologik kasalliklar
statistik to‘plami. Toshkent: Respublika Onkologiya markazi nashriyoti.
