NEUROLOGICAL AND ALLERGO-IMMUNOLOGICAL INDICATORS CHILDREN WITH HELMINTHIC INVASION
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hymenolepiasis, children, dynamics, immunology.##article.abstract##
A detailed analysis of the main clinical and laboratory parameters in groups of children suffering from allergic rhinitis (AR) with concomitant hymenolepiasis during antiallergic, antiparasitic and complex therapy is given. Patients with AR with
hymenolepidoses were divided into three groups: 21 patients received antiallergic therapy, 22 patients received antiparasitic therapy, and 24 patients underwent complex therapy. The maximum clinical effect was achieved by us with the use of complex
treatment, which included antiallergic and antiparasitic therapy.
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1.
CNS damage due to parasitic intoxication in children with helminthic and
protozoal infestations manifested as convulsive syndrome (52.9±5.9%), tic
hyperkinesis (25.7±5.2%), and autonomic dysfunction syndrome (ADS) (21.4±4.9%),
whereas in children with isolated giardiasis, these manifestations appeared as tic
hyperkinesis (14±4.9%) and ADS (86±4.9%).
2.
In cases of combined giardiasis and hymenolepiasis, neurological
complications were accompanied by a sympathetic orientation of tone and reactivity,
with a higher severity score for ADS. In children with isolated giardiasis, neurological
complications were mostly associated with parasympathetic predominance.
3.
The formation of secondary immunodeficiency was primarily due to the
suppression of T-helper and suppressor components, as well as B-lymphocytes, with
more pronounced effects in children with a combined infestation of giardiasis and
hymenolepiasis.
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