ONKOGENEZ

##article.authors##

  • Sapayeva Mahbuba Ulug’bekovna ##default.groups.name.author##
  • Sobirova Munisa Ismoiljon qizi ##default.groups.name.author##
  • Atoyev Azizbek Barno o’g’li ##default.groups.name.author##

##semicolon##

This article explores the process of oncogenesis, its stages, and biochemical foundations. The effects of genetic and epigenetic changes on cell proliferation, the roles of oncogenes and tumor suppressor genes are analyzed

##article.abstract##

Ushbu maqolada onkogenez jarayoni, uning bosqichlari va biokimyoviy asoslari yoritilan. Genetik va epigenetik o‘zgarishlarning hujayra proliferatsiyasiga ta’siri, onkogenlar va tumor suppressor genlarning roli tahlil qilingan. Shuningdek, onkologik 
kasalliklarni davolashda qo‘llaniladigan zamonaviy usullar – kimyoterapiya, molekulyar nishonli terapiya, immunoterapiya va gen terapiyasi haqida ma’lumot berilgan. Tadqiqot natijalari saraton kasalligining oldini olish va uni samarali davolash 
strategiyalarini ishlab chiqishda muhim ahamiyatga ega. 

##submission.citations##

B. Alberts, A. Johnson, J. Lewis, M. Raff, K. Roberts, P. Walter. Molecular Biology

of the Cell. 6th edition. Garland Science, 2014.

Hanahan D., Weinberg R. A. Hallmarks of Cancer: The Next Generation. Cell, 2011.

144(5):646-674.

J. K. Armstrong, J. A. Rosenthal, A. D. Ochoa. Oncology: A Multidisciplinary

Approach to Cancer. 2nd Edition. McGraw-Hill Education, 2013.

F. J. Rous. Oncogenes and Cancer: From Basic Science to Therapy. Springer Science

& Business Media, 2013.

H. W. Thompson, L. J. Smith. Cancer: Principles and Practice of Oncology. 10th

edition. Lippincott Williams & Wilkins, 2015.

S. M. Lee, A. A. Lee. Immunotherapy in Cancer Treatment. Springer, 2020.B. V. C. Rao. Cancer Chemotherapy: Principles and Practice. Elsevier, 2017.

National

Cancer Institute (NCI). Cancer Topics: Cancer Treatment.

https://www.cancer.gov/about-cancer/treatment

T. P. King. Molecular Oncology: From Basic Science to Therapeutic Strategies. Wiley

Blackwell, 2018.

##submissions.published##

2025-05-14