MEDICINAL ANALYSIS OF THE PLANT GLYCYRRHIZA GLABRA
Keywords:
Keywords: Antimicrobial, antioxidant, antiproliferative, Glycyrrhiza glabra, medicinal plantsAbstract
Abstract
Objective: Alternative medicine has an important place in the fight against many
diseases in human history. The biological activity of Glycyrrhiza glabra L. was
investigated in this study. Material and Method: The root parts of the plant were
extracted with ethanol. Antioxidant and oxidant potentials were determined using Rel
Assay kits. Antimicrobial activity was tested against standard bacteria and fungus
strains using the agar dilution method. Antiproliferative activity was determined by
MTT test against Lung Carcinoma Cell Line (A549). Result and Discussion: As a result
of the studies, the TAS value of the plant was measured as 8.770±0.171, TOS value as
14.590±0.191 and OSI value as 0.167±0.005. Inhibition of the plant extract was
observed against standard bacteria and fungus strains at ranging from 50-200 µg/mL
concentrations. In addition, it was determined that the plant extract displayed strong
antiproliferative activity due to the increase in concentration. As a result of these
studies, it has been determined that G. glabra can be used as an important natural
antioxidant, antimicrobial and anticancer agent.
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