ACUTE UNCOMPLICATED CYSTITIS IN WOMEN: EPIDEMIOLOGY, DIAGNOSIS, AND EVIDENCE-BASED TREATMENT APPROACHES
Keywords:
Keywords: Acute cystitis, women, urinary tract infection, diagnosis, antibiotic resistance, epidemiology, treatment guidelinesAbstract
Abstract. Acute uncomplicated cystitis is one of the most encountered
infections among women, affecting millions annually. It is characterized by dysuria,
urinary frequency, and suprapubic discomfort without systemic signs of infection. A
substantial burden on public health systems has been attributed to this condition due to
its prevalence and recurrent nature. In this review, the epidemiological patterns,
diagnostic approaches, and evidence-based treatment options are outlined. Current
guidelines have been reviewed, and emerging therapies have been discussed. The
importance of antimicrobial stewardship has been emphasized in the context of rising
antibiotic resistance.
References
References:
1. Gupta, K., Hooton, T. M., Naber, K. G., et al. (2011). International clinical practice
guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in
women. “Clinical Infectious Diseases”, 52(5), e103–e120.
2. Medina, M., & Castillo-Pino, E. (2019). An introduction to the epidemiology and
burden of urinary tract infections. “Ther Adv Urol”, 11, 1756287219832172.
3. Wagenlehner, F. M. E., & Naber, K. G. (2012). Practical aspects of antimicrobial
therapy of complicated urinary tract infections. “J Antimicrob Chemother”,
67(Suppl 1), i29–i39.
4. Flores-Mireles, A. L., Walker, J. N., Caparon, M., & Hultgren, S. J. (2015). Urinary
tract infections: Epidemiology, mechanisms of infection and treatment options.
“Nature Reviews Microbiology”, 13(5), 269–284.