ANTIFOSFOLIPID SINDROMINI PATOGENEZI, DIAGNOSTIK MEZONLARI VA HOMILADORLIKDAGI ASORATLAR
Keywords:
Kalit so‘zlar: Antifosfolipidniy sindrom, HELLP sindromi, homila ko’tarolmaslik, perinatal asoratlar.Abstract
Kirish: Hozirgi davrda autoimmun kasalliklarning o‘sib borayotgan tarqalishi ularni erta tashxislash va davolash masalasini dolzarb muammolardan biriga aylantirmoqda. Shunday kasalliklardan biri bo‘lgan antifosfolipid sindromi (AFS), o‘zining murakkab patogenezi va ko‘p qirrali klinik ko‘rinishlari bilan ajralib turadi. Bu sindrom venoz va arterial trombozlar, nevrologik buzilishlar, yurak-qon tomir o‘zgarishlari, shuningdek, homiladorlikdagi og‘ir asoratlar bilan kechadigan autoimmun xastalikdir. Ayniqsa, reproduktiv yoshdagi ayollar orasida AFS’ning keng tarqalganligi, takroriy homila yo‘qotishlar, preeklampsiya, platsentaning erta ajralishi, homila o‘sishining cheklanishi kabi akusherlik patologiyalarining rivojlanishida asosiy etiologik omil sifatida ko‘rilmoqda.
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