TARQOQ SKLEROZ VA NEYRODEGENERATSIYA, KOGNITIV BUZILISHLARNI BASHORAT QILISHDA BIOMARKERLARNING O‘RNI
##semicolon##
Tarqoq skleroz, neyrodegeneratsiya, kognitiv buzilishlar, biomarkerlar, neyrofilament yengil zanjiri.##article.abstract##
Ushbu maqolada tarqoq skleroz (TS)da kognitiv buzilishlarni
bashorat qilishda biomarkerlarning diagnostik va prognostik ahamiyati yoritilgan.
Tadqiqotda neyrofilament yengil zanjiri (NfL) va glial fibrillyar kislotali oqsil (GFAP)
darajalari tahlil qilinib, ularning neyrodegeneratsiya va kognitiv yetishmovchilik bilan
bog‘liqligi
aniqlangan.
Neyrovizualizatsiya
ma’lumotlari
biomarkerlar
konsentratsiyasi bilan miya korteksining atrofiya darajasi o‘rtasidagi bog‘liqlikni
ko‘rsatadi. Maqola TS bilan og‘rigan bemorlarda shaxsiylashtirilgan monitoring
strategiyalarini ishlab chiqish uchun klinik amaliyotda ushbu biomarkerlarning
ahamiyatini asoslaydi.
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