TREATMENT RELATED MORTALITY IN ADOLESCENTS AND YOUNG ADULTS WITH ACUTE LYMPHOBLASTIC LEUKEMIA
Ключевые слова:
Key words: Acute lymphoblastic leukemia (ALL), treatment related mortality, remission induction, Philadelphia chromosome.Аннотация
Introduction: Acute lymphoblastic leukemia is a malignant disease classified on the basis of B cell versus T cell lineage. More than two thirds of cases of ALL are B cell phenotype. B cell ALL is primarily a disease of children less than 6 years old and second peak in adults more than 60 years. T cell ALL presents in late childhood and adolescents. Both B and T cell ALL occur more frequently in males than females. The cause of ALL is unknown but it may be associated with ionizing radiation and unidentified infectious agents.
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