ODAM TANASIDAGI MIKROBIOTA VA STRESS GORMONLARI O‘RTASIDAGI O‘ZARO BOG‘LIQLIK: YANGI ILMIY YONDASHUV
Ключевые слова:
Kalit so‘zlar: mikrobiota, stress gormonlari, kortizol, gut-miya o‘qi, neyroendokrin tizim, metagenomika, ruhiy salomatlik.Аннотация
Annotatsiya: Ushbu maqolada odam tanasidagi mikrobiota va stress gormonlari – xususan kortizol – o‘rtasidagi o‘zaro ta’sir mexanizmlari tahlil qilinadi. Mikrobiota ichki muhit barqarorligi va ruhiy salomatlikni ta'minlashda muhim rol o‘ynaydi. Tadqiqotda mikrobiomaning stressga qarshi fiziologik javoblarda ishtirok etish mexanizmlari, shuningdek, mikrobiota-gut-miya o‘qi doirasidagi neyroendokrin aloqa tahlil qilinadi. Tahlillar stress darajasining oshishi mikrobiomaning turli xil qismlarini izdan chiqarishi va bu orqali salomatlikka salbiy ta’sir qilishini ko‘rsatdi. Yangi ilmiy yondashuvlar va metagenomika vositalari orqali mikrobiota salomatlikdagi o‘rnini chuqurroq o‘rganish imkoniyatlari kengaymoqda.
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