PATHOLOGICAL PHYSIOLOGY OF POSTHEMORRHAGIC ANEMIA
Keywords:
Keywords: blood vessels, posthemorrhagic anemia, hemoglobin, hematocrit, blood pressure.Abstract
Annotation. Blood loss is a compleх of pathological disorders and
compensatory reactions directed against a decrease in the volume of circulating blood
and hypoxia caused by a decrease in the respiratory function of the blood.
Posthemorrhagic shock is a shock that occurs as a result of abundant acute blood loss.
A decrease in the volume of circulating blood, a drop in blood pressure, a violation of
microcirculation, disorders of the blood supply to vital organs (brain, heart, kidneys),
the development of hypoxia, acidosis and intoxication, "vicious circles" in the
pathogenesis leads to death. Post-hemorrhagic anemia-develops as a result of blood
loss.
References
References:
1. Kornblith LZ, Moore HB, Cohen MJ. Trauma-induced coagulopathy: The past,
present, and future. J Thromb Haemost. 2019 Jun;17(6):852-862.
2. Karasu E, Nilsson B, Köhl J, Lambris JD, Huber-Lang M. Targeting Complement
Pathways in Polytrauma- and Sepsis-Induced Multiple-Organ Dysfunction. Front
Immunol. 2019;10:543.
3. Deng M, Scott MJ, Fan J, Billiar TR. Location is the key to function: HMGB1 in
sepsis and trauma-induced inflammation. J Leukoc Biol. 2019 Jul;106(1):161-169.
4. Eastridge BJ, Holcomb JB, Shackelford S. Outcomes of traumatic hemorrhagic
shock and the epidemiology of preventable death from injury. Transfusion. 2019
Apr;59(S2):1423-1428.
5. Tang J, Shi Z, Hu J, Wu H, Yang C, Le G, Zhao J. Optimal sequence of surgical
procedures for hemodynamically unstable patients with pelvic fracture: A network
meta-analysis. Am J Emerg Med. 2019 Apr;37(4):571-578.
6. Scerbo MH, Holcomb JB, Taub E, Gates K, Love JD, Wade CE, Cotton BA. The
trauma center is too late: Major limb trauma without a pre-hospital tourniquet has
increased death from hemorrhagic shock. J Trauma Acute Care Surg. 2017
Dec;83(6):1165-1172.
7. Erdman MO, Chardavoyne P, Olympia RP. School Nurses on the Front Lines of
Medicine: The Approach to a Student With Severe Traumatic Bleeding. NASN Sch
Nurse. 2019 Sep;34(5):280-286.
