CONTRAST AGENTS IN RADIOLOGY: TYPES, RISKS AND PRECAUTIONS
Keywords:
Keywords: contrast agents, radiology, patient safety, adverse reactions, imaging enhancementAbstract
Abstract
Contrast agents are essential pharmaceutical compounds used in medical
imaging to enhance the visualization of anatomical structures and pathological
processes. This review examines the various types of contrast agents employed in
radiology, their associated risks, and the necessary precautions to ensure patient safety.
Understanding the proper selection, administration, and monitoring of contrast agents
is crucial for optimizing diagnostic accuracy while minimizing adverse effects. This
article provides a comprehensive overview of iodinated contrast media, gadolinium-
based agents, barium compounds, and newer contrast materials, along with evidence-
based guidelines for their safe clinical application.
References
References
1. Katayama H, Yamaguchi K, Kozuka T, et al. Adverse reactions to ionic and
nonionic contrast media: a report from the Japanese Committee on the Safety of
Contrast Media. Radiology. 1990;175(3):621-628.
2. Morcos SK, Thomsen HS, Webb JA. Contrast-media-inducednephrotoxicity: a
consensus report. European Radiology. 1999;9(8):1602-1613.
3. Thomsen HS, Morcos SK, Almén T, et al. Nephrogenic systemic fibrosis and
gadolinium-based contrast media: updated ESUR Contrast Medium Safety
Committee guidelines. European Radiology. 2013;23(2):307-318.
4. ACR Committee on Drugs and Contrast Media. ACR Manual on Contrast Media
Version 10.3. American College of Radiology; 2018.
5. Barrett BJ, Carlisle EJ. Metaanalysis of the relative nephrotoxicity of high- and low-
osmolality iodinated contrast media. Radiology. 1993;188(1):171-178.
